Bioink In 3D Printing

  • 3D Bioprinting is one of the most advanced technologies that has emerged in the last couple of years.
  • In recent years new materials e.g., Bioinks are used to produce artificial living tissues using 3D bio-printing.
  • Bioinks are human derived biomaterials such as hydrogels, gelatin, collagen, extracellular matrix-based materials.
Image source – https://biotechconnectionbay.org/viewpoint/how-3d-bioprinting-complements-the-healthcare-and-pharmaceutical-industries/

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Products Related to Bio-ink

product related to bioink

Interesting Research Articles Related To Bioink & Bioprinting

3D bioprinted silk fibroin hydrogels for tissue engineering

  • This article deals with the methacrylated photocurable silk fibroin (SF) bioink for digital light processing 3D bioprinting to generate structures with high mechanical stability and biocompatibility for tissue engineering applications.
  • The versatile bioink can be used broadly in a range of applications, including nerve tissue engineering through co-polymerization of the bioink with graphene oxide, and for wound healing as a sealant.

Bioinks for 3D Bioprinting: A Scientometric Analysis of Two Decades of Progress

  • The present review article reveals about the use and development in the bioink used for 3D bioprinting.bioink pie chart img2
  • Alginate and gelatin methacryloyl are the most popular hydrogels.

Patenting Trends

The below Pie chart states the number of patents published in selected WO, US, IN. There are 16 PCT Patent publications, 04 US patent publications and 02 Indian publications.

The below bar graph represents the top 6 materials used in Bioink for 3D bioprinting and their respective patent count in WO, US, IN. Collagen is the most commonly used material.

Conclusion

  • 3D bioprinting is the most promising technology for organ transplantation.
  • Synthetic organs or tissues can be created using a bioink which is composed of living cells and naturally derived polymers.
  • In the recent years, this technique has emerged a lot and many of the companies have manufactured advanced bioinks and bioprinters. Some of the companies are- Foldink, CollPlant, Jellagen, Rousselot, Humabiologics, 4D Biomaterials, UPM Biomedicals, INNOREGEN, HumaDerm etc.
  • Collagen, cellulose, hydrogels, gelatin, Tissue ECM, Organ ECM etc. are most common bioink materials.
  • Alginate and gelatin methacryloyl are the most popular hydrogels.
  • Summarizing the study, we can conclude that Bioinks are booming now days for organ transplantation, drug discovery, cancer research, tissue engineering and regenerative medicine.

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